Jingdong Yumei Kidney Disease Hospital

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The Treatment of Adult Lupus Nephritis

Plasma Exchange, as one of the dominant blood purification methods, it is said to have great effects in treating adult Lupus Nephritis through removing circulating immune complexes, auto antibodies such as anti-double-stranded DNS, anti-SSA and other immune reactants. These immune complexes deposit in kidney and cause inflammatory response which is the direct cause for kidney damages.

Therefore, by clearing them away, no immune complexes lodge in kidney again and consequently, Lupus Nephritis can be controlled to some extent.

However, some people have different attitude toward efficacy of plasma exchange in patients with Lupus Nephritis by holding the idea that the so called antibody and immune complexes will occur after stopping plasma exchange. Also, it is said Plasma Exchange is useful in a small group of Lupus Nephritis patients.

As a matter of fact, plasma exchange can’t be regarded as a dominant treatment for Lupus Nephritis, as it only remains helpful in cleaning blood and fail to repair kidney damages. In case of Lupus Nephritis, aside from clearing immune complexes away from blood, repairing kidney damages is the key point for sufferers to recover as well as avoid kidney failure. Thereby, plasma exchange is not a permanent therapy for Lupus Nephritis, but a temporary treatment.